Zytoreduktive Chirurgie und hypertherme intraperitoneale Chemotherapie beim Magenkarzinom
| Autor: | Felix Gronau, Linda Feldbrügge, Beate Rau, Vincent Wolf, Alan Oeff, Maximilian Jara |
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| Rok vydání: | 2021 |
| Předmět: |
Oncology
Hyperthermia medicine.medical_specialty business.industry Cancer Perioperative medicine.disease Peritoneal carcinomatosis 03 medical and health sciences 0302 clinical medicine Cardiothoracic surgery 030220 oncology & carcinogenesis Internal medicine medicine 030211 gastroenterology & hepatology Surgery Hyperthermic intraperitoneal chemotherapy Cytoreductive surgery business Abdominal surgery |
| Zdroj: | Der Chirurg. 92:522-527 |
| ISSN: | 1433-0385 0009-4722 |
| DOI: | 10.1007/s00104-021-01371-3 |
| Popis: | Background Gastric cancer with peritoneal metastases is associated with an extremely poor prognosis. Developed multimodal treatment concepts, which include a combination of perioperative systemic treatment and cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (HIPEC), show promising results with respect to improvement of the long-term survival. Methods This article contains a review of the literature of published studies on the topic of gastric cancer and peritoneal metastasis. Results The prognosis of patients with gastric cancer peritoneal carcinomatosis shows an extremely limited median survival of 7 months under palliative second-line systemic treatment. The median survival time increased to 12 months with cytoreductive surgery and in combination with HIPEC showed a positive effect on survival in individual studies. Expert opinion Treatment recommendations for patients with peritoneal metastases of gastric cancer should be carried out by experts in surgical reference centers. |
| Databáze: | OpenAIRE |
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