Studies of calcium phosphate cements for clinical applications in oral and maxillofacial surgery. Report II: An experimental study of hardened .ALPHA.-TCP/DCPD/TeCP cement in rabbits
| Autor: | Masahiro Hirano, Toshikazu Minemura, Hiroshi Kurita, Akira Kotani, Kenji Kurashina, Hiroichi Kobayashi |
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| Rok vydání: | 1996 |
| Předmět: | |
| Zdroj: | Japanese Journal of Oral & Maxillofacial Surgery. 42:822-828 |
| ISSN: | 2186-1579 0021-5163 |
| DOI: | 10.5794/jjoms.42.822 |
| Popis: | A new system of calcium phosphate cement, consisting of α-tricalcium phosphate (α-TCP), dicalcium phosphate dibasic (DCPD), and tetracalcium phosphate (TeCP), was developed. In this study, columns of hardened cement were implanted on the inferior surface of rabbit mandibles and into the back muscle for 6 months, 1 year, and 1.5 years to evaluate responses of the surrounding tissues and changes in the materials in vivo.Histologic, microradiographic and scanning electron micrographic investigations of the implants in mandibles revealed active bone formation along the surface of the cement and direct contact between new bone and the materials. The cement showed surface irregularities created by resorption, which were remarkable on surfaces bounded by soft tissue.Histologic and microradiographic studies of the implants in back muscles showed the presence of a thin fibrous capsule without inflammatory cell infiltration; resorption was usually more remarkable than that with materials implanted in mandibles.The results of this study suggest that the hardened cement is resorbable in vivo and is highly biocompatibile with living tissues. |
| Databáze: | OpenAIRE |
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