Toxicity of intraperitoneally injected formalin in Atlantic salmon, Salmo salar L

Autor:	H. Nilsem, T Taksdal, Atle Lillehaug, R. Nordmo
Rok vydání:	1992
Předmět:	Veterinary medicine medicine.medical_specialty Veterinary (miscellaneous) Chlorbutol Aquatic Science Biology biology.organism_classification Body weight Surgery Benzocaine Toxicity medicine Fish Salmo medicine.drug
Zdroj:	Journal of Fish Diseases. 15:323-329
ISSN:	1365-2761 0140-7775
DOI:	10.1111/j.1365-2761.1992.tb00670.x
Popis:	Atlantic salmon, Salmo salar L., parr were injected intraperitoneally with different quantities of formalin (37% formaldehyde) following anaesthetization with either benzocaine (ethyl-p-aminobenzoate) or chlorbutol (1,1,1,-trichloro 2-methyl-2-propanol) The LD50 for injected formaldehyde was found to be approximately 50mg kg−1 body weight. The type and concentration of the anaesthetic used did not influence mortality rates. Formalin is commonly used to inactivate microorganisms in vaccines. Doses of formalin which were shown to be toxic in this study are close to those which may be injected into fish as a component of various vaccines against bacterial fish diseases. Hence, the formalin content in fish vaccines may well cause mortality under certain conditions.
Databáze:	OpenAIRE
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