Tuberculosis Treatment Outcomes and Determinants among Patients Treated in Hospitals in Imo State, Nigeria
Autor: | Kenechi A. Uwakwe, Chinomnso C Nnebue, Irene A. Merenu, Chinedu Anthony Iwu, Chioma A. Duru, Chukwuma B. Duru, Chima O. Emerole, KC Diwe |
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Rok vydání: | 2016 |
Předmět: |
0301 basic medicine
Pediatrics medicine.medical_specialty education.field_of_study Tuberculosis business.industry 030106 microbiology Treatment outcome Population Developing country Disease medicine.disease 03 medical and health sciences 0302 clinical medicine Pulmonary tuberculosis Medicine Sputum Effective treatment 030212 general & internal medicine medicine.symptom business education |
Zdroj: | OALib. :1-17 |
ISSN: | 2333-9705 2333-9721 |
Popis: | Introduction: Tuberculosis is a highly feared disease, known for centuries to affect, debilitate, impoverish large sections of the population and continues to ravage the world and especially the developing world. TB is curable and its effective treatment has shown a significant effect on the control of the disease. Methodology: This was a retrospective hospital based study carried out on records of 1025 TB cases, treated from 2009-2012 cohorts. A structured proforma was used to collect information from the TB registers, individual cards and folder records of the patients. Data were analyzed using a software package, EPI INFO version 7.1.3. Frequencies tables and summary indices were generated and chi-square was used to test association between variables where appropriate. P-value of ≤0.05 was considered significant. Results: Most of the cases reviewed had pulmonary tuberculosis. 96.7% and majority (86.3%) of them had sputum smear positive results at diagnosis. Majority, 79.7% of the patients were new cases and the treatment outcome showed a total success rate of 81.4%, (cured, 46.3% and completed treatment, 35.1%), default, (9.8%), died (6.5%) and failed treatment (1.5%). Factors found to significantly affect treatment outcome in this study were; age, gender, educational status, religion, living with someone, treatment regimen, HIV status of patients and type of patient at presentation/diagnostic criteria, p < 0.05. Conclusion: The success rate recorded in this study was below the set target by WHO, thus there was a need to put in place appropriate measures to improve the outcome of TB treatment in Imo State, Nigeria. |
Databáze: | OpenAIRE |
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