| Autor: |
Ju Yuel Park, Young Whan Kim, Young Kyun Choe, Chee Mahn Shin, Kun Moo Lee, Seo Yong Kim, Jin Woo Park, Young Jae Kim, Soon Ho Cheong |
| Rok vydání: |
2002 |
| Předmět: |
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| Zdroj: |
Korean Journal of Anesthesiology. 43:575 |
| ISSN: |
0302-5780 |
| DOI: |
10.4097/kjae.2002.43.5.575 |
| Popis: |
Background: In intravenous administration of a depolarizing neuromuscular blocker, succinylcholine is reported to produce activation of the electroencephalogram and increase cerebral blood flow and intracranial pressure. In this point, rocuronium was recently introduced as a non-depolarizing relaxant, and recommended as a safe alternative to succinylcholine. The purpose of this study was to evaluate the effects of rocuronium and succinylcholine on cerebral blood flow velocities during anesthetic induction. Methods: Forty patients were randomly assigned into two groups. Group 1 was administrated rocuronium 0.6 mg/kg and group 2 was administrated succinylcholine 1 mg/kg for tracheal intubation after each group had intravenous administration of thiopental 5 mg/kg. The author observed changes of mean arterial pressure, arterial carbon dioxide tension, and middle cerebral arterial blood flow velocities at 5 times: before induction (control), 30 sec after thiopental administration, 30 sec, 60 sec and 90 sec after muscle relaxant administration. Results: Mean arterial pressure decreased more at 30 sec after thiopental administration compared with the control (P |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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