A study on anti dermatophytic potential of selected ethno medicinal plants against Trichophyton rubrum, a common etiologic agent in and around Visakhapatnam region (India)
| Autor: | A Nagamani, I. Jyothi Padmaja, Y Nagendra sastry, T. Sai Devi |
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| Rok vydání: | 2012 |
| Předmět: |
Traditional medicine
biology Couroupita guianensis food and beverages Trichophyton rubrum biology.organism_classification medicine.disease_cause complex mixtures Biochemistry Genetics and Molecular Biology (miscellaneous) Cassia visual_art visual_art.visual_art_medium Dermatophyte medicine Bark Trichophyton skin and connective tissue diseases Annona Medicinal plants |
| Zdroj: | Asian Pacific Journal of Tropical Biomedicine. 2:S1874-S1878 |
| ISSN: | 2221-1691 |
| Popis: | Objective The purpose of this study was to evaluate the clinical patterns and etiology of dermatophytosis and the anti dermatophytic potentiality of some selected medicinal plants used by tribal people in and around Visakhapatnam region, India. Methods 62 patients with dermatophytosis who attended the dermatology clinic of King George hospital, Visakhapatnam were studied. Isolation and identification was done by direct microscopic observation, cultural characteristics and by using biochemical tests in the microbiology laboratory. Some ethno medicinal plant parts like Albizia lebbeck bark, Annona reticulata leaf and bark, Cassia fistula leaf, Wrightia tinktoria bark and Couroupita guianensis leaf were tested for anti dermatophytic activity by agar well diffusion method and minimum inhibitory concentration (MIC) studies were carried out by broth dilution assay. Results 51 patients out of 62 were positive (82.2%) by direct smear and culture. Tinea corporis was the most common dermatophytosis which was predominantly caused by Trichophyton rubrum in and around Visakhapatnam. Two dermatophyte species were isolated and identified. Trichophyton rubrum was the most frequent isolate (58.8%) followed by Trichophyton mentagrophytes (19.6%). Albizia lebbek bark, Annona reticulata bark and leaf extracts showed inhibitory against T. rubrum while Cassia fistula leaf extract did not show significant inhibitory activity. Wrightia tinktoria bark and Couroupita guianensis leaf extracts did not show inhibitory activity. Conclusions The results showed that tinea corporis was the most common dermatophytosis in and around Visakhapatnam region. Trichophyton rubrum was the most common etiologic agent. Albizia lebbek bark, Annona reticulata leaf and bark extracts showed potential inhibitory activity against Trichophyton rubrum than other tested ethno medicinal plants. |
| Databáze: | OpenAIRE |
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