Role of Na,K-ATPase in absorption of isotonic fluid by frog gall bladder epithelium

Autor: O. N. Kharlamova, M. S. Yaremenko
Rok vydání: 1978
Předmět:
Zdroj: Bulletin of Experimental Biology and Medicine. 85:555-558
ISSN: 1573-8221
0007-4888
DOI: 10.1007/bf00806369
Popis: Experiments on isolated frog gall bladders showed that the addition of ouabain (1·10−4 M) or noradrenalin (3·10−6 M) to the incubation Ringer's solution from the side of the serous surface of the organ or replacement of the K+ in the solution by the equivalent Na+ concentration causes a decrease in the rate of absorption of fluid by the epithelium and a decrease in the Na,K-ATPase activity in its cells. Noradrenalin reduces Mg-ATPase activity also. Significant positive correlation was found between the rate of transport of isotonic fluid by the epithelium and the Na,K-ATPase activity in its cells.
Databáze: OpenAIRE