Role of Na,K-ATPase in absorption of isotonic fluid by frog gall bladder epithelium
Autor: | O. N. Kharlamova, M. S. Yaremenko |
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Rok vydání: | 1978 |
Předmět: | |
Zdroj: | Bulletin of Experimental Biology and Medicine. 85:555-558 |
ISSN: | 1573-8221 0007-4888 |
DOI: | 10.1007/bf00806369 |
Popis: | Experiments on isolated frog gall bladders showed that the addition of ouabain (1·10−4 M) or noradrenalin (3·10−6 M) to the incubation Ringer's solution from the side of the serous surface of the organ or replacement of the K+ in the solution by the equivalent Na+ concentration causes a decrease in the rate of absorption of fluid by the epithelium and a decrease in the Na,K-ATPase activity in its cells. Noradrenalin reduces Mg-ATPase activity also. Significant positive correlation was found between the rate of transport of isotonic fluid by the epithelium and the Na,K-ATPase activity in its cells. |
Databáze: | OpenAIRE |
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