| Popis: |
F -alkyl chains perturb the reactivity of substrates in an often unpredictable way. F -alkyl azirine and aziridine carboxylates were prepared from F -alkynylesters, in 80 and 60% yield, respectively, and were found to display reactivities different from those of their hydrocarbon analogs. Thus, F -alkylazirines ( 5 ) give addition products easily but resist ring opening, while the F -alkylaziridines ( 8 ) are extremely stable, both towards nucleophilic and electrophilic reagents and irrespective of the medium used, neutral, acid or basic. |
