Surgical and pharmacological reassignment: influence on transsexual cardiovascular risk profile
| Autor: | Carlo Bettocchi, Michele Gesualdo, Marcello Campagna, Giuseppe Loverro, Pietro Scicchitano, Santa Carbonara, Barbara Boninfante, Gabriella Ricci, Marco Matteo Ciccone, Matteo Loverro, Vittorio Nicolardi, Francesca Scaramuzzi, Annapaola Zito, Orlando Todarello, Francesca Cortese, Fabio Manca, Michele Moncelli |
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| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
business.industry Carotid arteries medicine.medical_treatment Urology 030209 endocrinology & metabolism Vasodilation 030204 cardiovascular system & hematology Risk profile Surgery Transsexual 03 medical and health sciences 0302 clinical medicine Hormone replacement therapy (female-to-male) medicine.artery cardiovascular system Internal Medicine medicine cardiovascular diseases Orchiectomy Hormone therapy Brachial artery business |
| Zdroj: | Internal Medicine Journal. 47:1255-1262 |
| ISSN: | 1444-0903 |
| DOI: | 10.1111/imj.13597 |
| Popis: | Introduction The aim was to evaluate and stratify early cardiovascular risk of transsexuals undergone pharmacological and/or surgical gender reassignment. Methods Fifty-six transsexuals were divided into two groups: 1- undergone gonadectomy (orchiectomy for trans women and hystero-annessiectomy for trans men); group 2- hormone replacement therapy alone. All underwent carotid artery intima-media thickness (C-IMT) and flow-mediated vasodilation (FMD) of brachial artery evaluations. Results FMD was lower in patients undergone gonadectomy as compared to not- surgically treated patients (Group 1: 5.711 vs Group 2: 7.339, p |
| Databáze: | OpenAIRE |
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