The diagnosis and treatment of acquired Myasthenia Gravis in two adult dogs using oral neostigmine bromide

Autor:	Y.U. Senapathi, Indira Silva, Wrb Kumara, W. C. R. Fernando, M.D.H.S. Mallikarachchi, W.G.D.A. Gunathilaka, D.R.A. Dissanayake, E. Rajapaksha, D. D. N. de Silva
Rok vydání:	2016
Předmět:	Globulin biology business.industry Albumin medicine.disease Response to treatment Myasthenia gravis Neostigmine chemistry.chemical_compound chemistry Oral administration Bromide Anesthesia Prednisolone medicine biology.protein business medicine.drug
Zdroj:	Sri Lanka Veterinary Journal. 63:27
ISSN:	2279-2090 2279-2074
DOI:	10.4038/slvj.v63i1.5
Popis:	Two adult dogs aged 3.5 and 9 years were diagnosed with acquired Myasthenia Gravis (MG) based on clinical signs and positive response to oral neostigmine bromide (0.25mg/Kg BW) within 4 hours of oral administration. Both patients were successfully treated using neostigmine (1mg/Kg BW daily) alone or with neostigmine (1mg/Kg BW daily) and prednisolone (1mg/Kg BW, q12h) combination. Serum alkaline phosphatase and albumin/ globulin ratio monitored in one of the above patients starting from one month prior to development of generalized clinical signs until complete recovery, showed significant alterations which can be used in diagnosing MG and in monitoring the response to treatment.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f98a871600485aa205b83e586643e862 https://doi.org/10.4038/slvj.v63i1.5 Zobrazit plný text záznamu