A comparison of cyclophosphamide, adriamycin, and 5-fluorouracil (CAF) and cyclophosphamide, methotrexate, 5-fluorouracil, vincristine, and prednisone (CMFVP) in patients with advanced breast cancer

Autor:	John T. Carpenter, Alfred A. Bartolucci, Stephen Krauss, Richard V. Smalley, Charles L. Vogel, John Lefante
Rok vydání:	1983
Předmět:	Oncology Cancer Research medicine.medical_specialty Vincristine Cyclophosphamide business.industry Cancer Combination chemotherapy medicine.disease Regimen Breast cancer Fluorouracil Prednisone Internal medicine medicine business medicine.drug
Zdroj:	Breast Cancer Research and Treatment. 3:209-220
ISSN:	1573-7217 0167-6806
Popis:	The Southeastern Cancer Study Group, in a prospectively randomized study involving patients with advanced breast cancer, has compared a low dose intermittently administered five-drug regimen including cyclophosphamide, methotrexate, 5-fluorouracil, vincristine, and prednisone (CMFVP) with an aggressively administered three-drug regimen including cyclophosphamide, doxorubicin, and 5-fluorouracil (CAF). CAF induced more responses and more complete responses and a longer duration of disease control. However, only a marginal difference was demonstrated in overall survival between the two regimens (p =
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f984c525f564146b40860b13fe9a0e19 https://doi.org/10.1007/bf01803563 Zobrazit plný text záznamu Full text from SpringerLink