Effect of constant infusion of gonadotropin releasing hormone (GnRH) agonist Buserelin and antagonist CDB 2085 A using osmotic minipumps on testicular function in adult male bonnet monkey (Macaca radiata): Einfluß einer konstanten Infusion des GnRH-Agonis

Autor:	R. Chakraborti, N. Ravindranath, A. Jagannadha Rao, S. G. Kotagi
Rok vydání:	2009
Předmět:	Agonist medicine.medical_specialty Adult male business.industry medicine.drug_class Urology Antagonist General Medicine Gonadotropin-releasing hormone Testicle Buserelin Testicular function Endocrinology medicine.anatomical_structure Internal medicine medicine business medicine.drug Hormone
Zdroj:	Andrologia. 22:567-573
ISSN:	1439-0272 0303-4569
DOI:	10.1111/j.1439-0272.1990.tb02056.x
Popis:	The effect of chronic infusion of gonadotropic hormone agonist Buserelin or antagonist CDB 2085 A for 15 weeks via alzet minipumps in adult male bonnet monkeys was studied. Infusion of Buserelin resulted in a decrease in the difference between serum testosterone values at 22.00 hours and 10.00 hours, decrease in responsiveness to injected Buserelin as judged by change in serum testosterone values from pre-injection values and decrease in sperm counts. Infusion of antagonist resulted in a decrease in the difference between serum testosterone values at 22.00 hours and 10.00 hours.
Databáze:	OpenAIRE
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