| Popis: |
Sodium (allyl 3-deoxy-α- d - lyxo -2-heptulopyranosid)onate ( 6 ), allyl 3-deoxy-β- and -α- d - manno -2-octulopyranoside, sodium (allyl 3-deoxy-β- l - gulo -2-octulopyranosid)onate, sodium (allyl α- d - glycero - d - talo -2-ocutulopyranosid)onate, sodium (allyl α- d - glycero - d - galacto -2-octulopyranosidonate, ammonium (allyl 3-deoxy-4- O - and -5- O -phosphono-α- d - manno -2-octulopyranosid)onate, and ammonium (allyl 3-deoxy-4- O - and -5- O -phosphono-β- d - manno -2-octulopyranosid)onate were prepared and copolymerized with acrylamide to give multivalent haptens, which were used in immune inhibition assays. The monoclonal antibody A 20, directed against α-pyranoside Kdo residues, did not react with these compounds, except with heptulosonic acid derivative 6 , thus proving that the terminal hydroxymethyl group of Kdo is not required for binding. |
