Comparison of Curative Effect of Cryosupernatant and Fresh Frozen Plasma at Complex Treatment of Disseminated Intravascular Coagulation Syndrome in Patients with Severe Concomitant Injury

Autor:	Evgeniy Aleksandrovich Tseymakh, A A Men'shikov, A V Bondarenko, S Yu Kuznetsov, I N Gontarev, I B Komleva, O I Smirnova, E A Tseimakh
Rok vydání:	2011
Předmět:	Disseminated intravascular coagulation Curative effect medicine.medical_specialty business.industry General Engineering Energy Engineering and Power Technology medicine.disease Gastroenterology Cryosupernatant Concomitant Internal medicine medicine In patient Fresh frozen plasma business
Zdroj:	N.N. Priorov Journal of Traumatology and Orthopedics. 18:49-53
ISSN:	2658-6738 0869-8678
DOI:	10.17816/vto201118449-53
Popis:	Results of comparative study of cryoplasmic therapy applied at complex treatment of 168 patients with disseminated intravascular coagulation syndrome were presented. In 56 patients complex therapy included cryosupernatant plasma (CSNP) and 112 patients received fresh frozen plasma (FFP). Study of coagulation and fibrinolysis system showed that restoration of fibrinolysis activity, physiologic anticoagulants and normalization of plasma fibrinogen levels occurred sooner when CSNP was used. Application of CSNP promoted the relaxation of disease severity, prevention of thrombotic complications and decrease of lethality (by 14.2%) to a greater extent as compared to FFP use.
Databáze:	OpenAIRE
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