Enantioselective separation of 1,4-disubstituted piperazine derivatives on two cellulose Chiralcel OD and OJ and one amylose Chiralpak AD chiral selectors

Autor:	Maria Mazgajska, Zdzisław Chilmonczyk, Hassan Y. Aboul-Enein, Hanna Ksycińska
Rok vydání:	1999
Předmět:	Pharmacology Steric effects Tris Organic Chemistry Enantioselective synthesis Catalysis Analytical Chemistry chemistry.chemical_compound Piperazine chemistry Drug Discovery Lipophilicity Organic chemistry Cellulose Enantiomer Selectivity Spectroscopy
Zdroj:	Chirality. 11:790-794
ISSN:	1520-636X 0899-0042
DOI:	10.1002/(sici)1520-636x(1999)11:10<790::aid-chir9>3.0.co;2-1
Popis:	A series of 1,4-disubstituted piperazine derivatives with hypnotic activity were examined on three polysaccharide-based chiral stationary phases, namely, Chiracel OD, Chiracel OJ and Chiralpak AD. It was possible to resolve all the compounds on all the phases examined (1.13
Databáze:	OpenAIRE
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