| Autor: |
Aniekanabasi Jonathan Okon, Olajumoke Esther Olanrewaju, Idorenyin Jonathan Okon, Simon Alain Inah, Olufemi Oludare Aluko, Afe Victor Dania |
| Rok vydání: |
2022 |
| Popis: |
Background Exposure to lead produces a variety of adverse health effects. This study evaluated the protective effect of Carica papaya leaves(CPL) and seed (CPS) against lead bioaccumulation in albino rats. Methods Thirty male rats weighing 174-196g were assigned to six groups of five animals receiving various treatments: group 1- control; 2-50mg/kg body weight (BW) lead nitrate (PbNO3); 3- 500 mg/kg BW CPL extract; 4- 500 mg/kg BW CPS extract; 5- 50mg/kg BW PbNO3 + 500mg/kg BW CPL; and 6- 50mg/kg BW PbNO3 + 500mg/kg CPS orally for 31 days. Results The study revealed a significant reduction (P 0.05) in the group complemented with CPS than CPL. Conclusion This finding suggests that CPL and CPS have the potential of reducing lead bioaccumulation and could be harnessed by pharmaceutical industries for this potential. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
