REVIEW: Metabolic Engineering of Isoprenoids

Autor:	Robert J. Barkovich, James C. Liao
Rok vydání:	2001
Předmět:	medicine.medical_specialty organic chemicals Genomic research Bioengineering Diterpenoid synthesis Computational biology Biology Applied Microbiology and Biotechnology Terpenoid Metabolic engineering Biochemistry Molecular genetics medicine Biotechnology Biosynthetic genes Pathway engineering
Zdroj:	Metabolic Engineering. 3:27-39
ISSN:	1096-7176
DOI:	10.1006/mben.2000.0168
Popis:	The metabolic engineering of natural products has begun to prosper in the past few years due to genomic research and the discovery of biosynthetic genes. While the biosynthetic pathways and genes for some isoprenoids have been known for many years, new pathways have been found and known pathways have been further investigated. In this article, we review the recent advances in metabolic engineering of isoprenoids, focusing on the molecular genetics that affects pathway engineering the most. Examples in mono- sequi-, and diterpenoid synthesis as well as carotenoid production are discussed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f95c0d3028c16d0f36a1bf143a48aec4 https://doi.org/10.1006/mben.2000.0168 Zobrazit plný text záznamu Full Text from ScienceDirect