Characterization of Gamma-Irradiated Rosmarinus officinalis L. (Rosemary)

Autor:	Alireza Alishahi, Reza Rezanejad, Mojtaba Raeisi, Marzieh Heidarieh, Gholamreza Rafiee, Seyed Mahdi Ojagh
Rok vydání:	2019
Předmět:	Materials science biology Pharmaceutical Science biology.organism_classification Rosmarinus Crystallinity Transmission electron microscopy Particle-size distribution Officinalis X-ray crystallography Molecular Medicine Irradiation Fourier transform infrared spectroscopy Nuclear chemistry
Zdroj:	Turkish Journal of Pharmaceutical Sciences. 16:43-47
ISSN:	2148-6247 1304-530X
DOI:	10.4274/tjps.37880
Popis:	Objectives Rosmarinus officinalis L., a member of the family Lamiaceae, is regarded as the spice with the highest antioxidant activity. Materials and methods In this study, the transmission electron microscopy, X-ray diffraction, and fourier transform infrared spectroscopy (FTIR) physicochemical characteristics of the nanostructure of gamma-irradiated rosemary were investigated. Results The particle size distribution of the gamma-irradiated rosemary prepared under irradiation at 30 kGy in a Cobalt-60 irradiator exhibited a very narrow size distribution with average size of 70 nm. The results showed that irradiated (30 kGy) and crude rosemary had similar patterns of FTIR spectra, typical of phenol compound, without any notable changes in the key bands and functional groups status. Rosemary irradiated with 50 kGy and 10 kGy showed the highest and lowest crystallinity, respectively. Rosemary crystallinity of irradiated samples was lower compared with the nonirradiated sample. Conclusion Therefore, 30 kGy can be optimum for the synthesis of nanoparticles, average size of 70 nm, with low crystallinity and without any notable change in key bands compared to nonirradiated samples.
Databáze:	OpenAIRE
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