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Palm-based nanoemulsion has played a significant role as a biocompatible delivery system in various industries, but has yet to achieve its full potential since little information about formulation with palm oil is known. Such a nanoemulsion can be developed and optimized systematically to attain excellent physicochemical properties, such as low viscosity, high kinetic stability, and large interfacial area, while being safe for human use. Most poorly water-soluble drugs could be loaded in this nanoemulsion and delivered efficiently to the target sites. This chapter summarizes recent studies conducted on the development of palm-based nanoemulsion, physicochemical characterization in contributing to drug efficacy, and in vitro permeation studies. Computational simulation study was used as a tool to investigate the self-assembly process and physicochemical properties at atomic details, based on experimentally phase diagrams obtained. Deeper understanding and research on nanodelivery via palm-based nanoemulsion will give positive impact, especially on the pharmaceutical industries. |
