A A COMPARATIVE STUDY OF QUALITY CONTROL TESTING ON CANDESARTAN CILEXETIL CONVENTIONAL TABLETS IN IRAQ

Autor: Karrar Mohammed Hasan Al-Gburi, Karrar Talib Khudhair Albo Hamrah, Abulfadhel Jaber Neamah Al-Shaibani, Sarmad Sabah Al-Edresi
Rok vydání: 2020
Předmět:
Zdroj: International Journal of Applied Pharmaceutics. :103-108
ISSN: 0975-7058
DOI: 10.22159/ijap.2020v12i2.36220
Popis: Objective: The present study was performed to compare the quality of conventional tablets loaded with candesartan cilexetil. The selected candesartan cilexetil tablets were commercialized in the Iraq market and produced by different companies. Methods: Different batches of candesartan cilexetil oral tablets (the concentration of candesartan was 8 mg) were subjected to quality control tests. Tests included weight variation, friability, hardness, drug content, disintegration time and in vitro release study. The protocols of these tests were performed according to USP pharmacopeia. Results: The results, in this study, revealed that all the used batches of candesartan cilexetil oral tablets complied with the specification of USP pharmacopeia for weight uniformity, friability value (% loss) was
Databáze: OpenAIRE