An Enriched Collagen Peptide Formula but not Fish Collagen Improves Exercise Performance and Metabolic Status in Old Mice
| Autor: | Kumar N, Naito Y, Lorenzetti A, Takadanohara H, Marotta C, Cervi J, Marotta F, Makida Y, Mohania D, Fang He |
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| Rok vydání: | 2018 |
| Předmět: |
Glycogen
Collagen peptide business.industry Skeletal muscle 030209 endocrinology & metabolism 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Animal science medicine.anatomical_structure chemistry Endurance training Exercise performance TBARS Medicine Fish Treadmill business 030217 neurology & neurosurgery |
| Zdroj: | Journal of Postgenomics Drug & Biomarker Development. |
| ISSN: | 2153-0769 |
| DOI: | 10.4172/2153-0769.1000198 |
| Popis: | Eighty twenty-four month old male mice, maintained under standardized conditions, were divided depending on dietary supply: A) standard age-balanced chow food and B) added with GPT-2218 (dosage to be worked out after preliminary data). Animals were weight-matched and each group randomly allocated to: s) a sedentary protocol or t) training protocol by applying endurance exercise. Namely, after adaptation in an ergometric treadmill for one week (5%, 6-8 m/min), the latter group was subjected to following schedule: 20 m/min, 8° slope, 50 min/day for the first week and 25 m/min, 8° slope, 50 min/day (corresponding to 75% of maximum VO2) for the second week. A further group, either sedentary or trained, was supplemented with a generic fish collagen-peptide compound(C) claimed of stamina effect. So, altogether six groups were examined as follows: As (standard food, sedentary), At (standard food under training), Bs (supplemented-sedentary), Bt (supplemented under training), Cs and Ct. Parameters measured were VO2max, liver and gastrocnemius tissue level of glycogen, gastrocnemius level of oxidative markers and inflammatory/anti-inflammatory balance. Results showed that as compared to At, where training showed only a trend improvement of VO2max, Bt had a significant improvement (p |
| Databáze: | OpenAIRE |
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