The Role of Cyclic Nucleotides in the Control of Anterior Pituitary Gland Activity
| Autor: | N. Barden, Raymonde Veilleux, M. Beaulieu, Helene Meunier, Johanie Lépine, L. Ferland, L. Lagace, M. Godbout, Vincent Giguère, V. Raymond, Jocelyne Massicotte, Borgeat P, J. Cote, J. Drouin, F. Labrie |
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| Rok vydání: | 1982 |
| Předmět: |
endocrine system
medicine.medical_specialty endocrine system diseases Chemistry Prolactin Cyclic nucleotide chemistry.chemical_compound medicine.anatomical_structure Endocrinology Anterior pituitary Hypothalamus Internal medicine medicine Secretion Luteinizing hormone Neurohormones hormones hormone substitutes and hormone antagonists Hormone |
| Zdroj: | Handbook of Experimental Pharmacology ISBN: 9783642683954 |
| DOI: | 10.1007/978-3-642-68393-0_12 |
| Popis: | The anterior pituitary gland secretes six known polypeptide hormones: ACTH (adrenocorticotropin), GH (growth hormone), PRL (prolactin), TSH (thyrotropin), LH (luteinizing hormone), and FSH (follicle-stimulating hormone). The rate of secretion of these individual polypeptides is specifically controlled by neurohormones released from the hypothalamus and transported to their adenohypophyseal site of action by a short portal blood system (Schally et al. 1968). The secretion of LH, FSH, and ACTH is known to be under only positive hypothalamic control, whereas that of GH, TSH, and PRL results from the balance of action of inhibitory and stimulatory neurohormones (Fig. 1). The overall influence of the hypothalamus on GH and TSH secretion is stimulatory, whereas it is inhibitory on PRL secretion. |
| Databáze: | OpenAIRE |
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