Administration of Anti-TNF Antibody Improves Left Ventricular Function in Septic Shock Patients
| Autor: | Jan Bakker, Gaëtan Marecaux, Jean Louis Vincent, Liliane Schandene, Robert J. Kahn, Etienne Dupont |
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| Rok vydání: | 1992 |
| Předmět: |
Pulmonary and Respiratory Medicine
medicine.medical_specialty Mean arterial pressure Resuscitation Septic shock business.industry Cardiac index Central venous pressure Critical Care and Intensive Care Medicine medicine.disease Surgery Anesthesia Shock (circulatory) medicine.artery Pulmonary artery Heart rate medicine medicine.symptom Cardiology and Cardiovascular Medicine business |
| Zdroj: | Chest. 101:810-815 |
| ISSN: | 0012-3692 |
| Popis: | In this pilot study, murine monoclonal anti-TNF antibody (2 mg/kg) was administered to ten patients within 24 h of septic shock which persisted after initial resuscitation with intravenous fluids and adrenergic agents. This treatment resulted in a reduction in heart rate (from 122 ± 10 to 113± 10 beats per minute at 4 h, p 2 at 2 h, p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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