Long-Term Outcome for Patients With High Volume Retroperitoneal Teratoma Undergoing Post-Chemotherapy Surgery

Autor: John P. Donohue, Richard Bihrle, Lawrence H. Einhorn, Stephen D.W. Beck, Richard S. Foster
Rok vydání: 2009
Předmět:
Zdroj: Journal of Urology. 181:2526-2532
ISSN: 1527-3792
0022-5347
DOI: 10.1016/j.juro.2009.01.116
Popis: Purpose: We determined outcomes in patients with testicular cancer with large volume (greater than 10 cm) retroperitoneal teratoma treated with post-chemotherapy retroperitoneal lymph node dissection.Materials and Methods: A retrospective review of our testicular cancer database was performed from 1995 to 2005 to identify patients undergoing post-chemotherapy retroperitoneal lymph node dissection for residual masses larger than 10 cm with final pathological examination revealing teratoma. A total of 99 patients met the study inclusion criteria.Results: A total of 27 patients presented with disease limited to the retroperitoneum, 46 had 2 or 3 disease sites and 26 had 4 or more disease sites. Mean and median hospital stay was 7.3 and 5.0 days, respectively. There were 23 recurrences in 27 locations with the most common being pulmonary in 5, mediastinal in 5 and retroperitoneal in 5. The 2 and 5-year disease-free survival was 86% and 75% with a mean followup of 42 months. The 2-year disease-free survival fo...
Databáze: OpenAIRE