Correlation of High Sensitive C Reactive Protein Levels as Inflammation Marker with Red Blood Cell Distribution Width Value in Regular Hemodialysis Patients at H. Adam Malik General Hospital
| Autor: | Alwi Thamrin Nasution, Radar Radius Tarigan, Anwar Sholeh |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Kidney biology business.industry medicine.medical_treatment C-reactive protein Red blood cell distribution width medicine.disease Gastroenterology medicine.anatomical_structure Internal medicine medicine biology.protein Renal replacement therapy Hemoglobin Hemodialysis business Dialysis Kidney disease |
| Zdroj: | International Journal of Research and Review. 8:14-27 |
| ISSN: | 2349-9788 2454-2237 |
| Popis: | Background: Chronic kidney disease (CKD) is characterized by structural and functional disorder of the kidney with irreversible and gradual characteristics with one of the modalities of renal replacement therapy such as hemodialysis (HD). The role of inflammation in HD patients by uremic toxin and dialysis can be assessed by the marker of High Sensitive C Reactive Protein (HsCRP). Several studies have examined the relationship between HsCRP and red cell distribution width (RDW) in regular HD patients which leads to increase patient morbidity and mortality, but until now, there has been no study in Indonesia regarding the correlation between HsCRP and RDW in regular HD patients. This study aims to determine the correlation HsCRP as a marker of inflammation and RDW values in regular HD patients. Methods: This is a cross-sectional study in Regular HD patients at Dialysis Unit-H. Adam Malik General Hospital. A total of 20 subjects were included. Bivariate and multivariate analysis was conducted to analyze the relationship of HsCRP, ureum, creatinin, hemoglobin, and eGFR to RDW. Results: There were 20 Regular HD patients analyzed. The proportion of patients with increased RDW was 80%. In pearson correlation test, there is a strong correlation between HsCRP and RDW (r= 0.667, p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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