Abstract 15267: 1-Year Survival Post Trans-Catheter Aortic Replacement in Patients With Low and High-gradient Severe Aortic Valve Stenosis

Autor:	Konstantinos Voudris, Jaafar Alward, Caleb Chiang, Mohamad Hemu, Hassam Suradi
Rok vydání:	2020
Předmět:	medicine.medical_specialty Ejection fraction business.industry medicine.disease Stenosis Catheter Physiology (medical) Internal medicine Aortic valve stenosis Cardiology medicine In patient Cardiology and Cardiovascular Medicine business
Zdroj:	Circulation. 142
ISSN:	1524-4539 0009-7322
Popis:	Introduction: There is limited data on trans-catheter aortic replacement (TAVR) outcomes in patients with low gradient-preserved ejection fraction aortic stenosis (LGpEF). Our study aims to compare baseline characteristics and procedural outcomes in patients with LGpEF vs. high gradient severe aortic stenosis (HGAS). Methods: Patients who underwent TAVR at our institution were divided in 2 groups: 1) HGAS (aortic valve area (AVA) < 1cm 2 , mean gradient (MG) > 40 mmHg); 2) LGpEF (AVA < 1cm 2 , MG Results: A total of 140 patients with HGAS (53% female, 81±9 years old) and 73 patients with LGAS (51% female, 80±9.5 years old) were identified. In multivariable analyses, there was no statistically significant difference in mortality between HGAS vs. LGpEF (HR 0.53, 95% CI 0.21-1.3; p=0.16) (Figure). PVL was independently associated with increased mortality in HGAS (HR 2.9, 95% CI 1.2-7.3; p=0.02) but this effect was not observed in patients with LGpEF. Conclusions: After adjusting for relevant patient characteristics, TAVR outcomes in patients with LGpEF were similar to those with HGAS at 1-year follow-up.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f8ba9638523310d851a3d8027c5b241e https://doi.org/10.1161/circ.142.suppl_3.15267 Zobrazit plný text záznamu