Cell signalling and bone remodelling Part II: Developments in the pathogenesis and principles of management of selected skeletal disease states
| Autor: | EJ Raubenheimer, C Noffke |
|---|---|
| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
Cell signaling Pathology medicine.medical_specialty Bone disease business.industry Osteoporosis 030209 endocrinology & metabolism Osteopetrosis Bone healing medicine.disease Bone remodeling Pathogenesis 03 medical and health sciences 030104 developmental biology 0302 clinical medicine Skeletal disease Medicine business Neuroscience |
| Zdroj: | The South African Orthopaedic Journal (SAOJ). 15:87-90 |
| ISSN: | 1681-150X |
| DOI: | 10.17159/2309-8309/2016/v15n1a11 |
| Popis: | Mapping of the bone remodelling signalling pathways contributed significantly to the establishment of a scientific basis for the development of pharmaceuticals which have the potential to induce or suppress bone formation. Enhancing bone healing and the establishment of a pre-determined skeletal phenotype are now within reach of the medical profession. This manuscript provides practitioners with an overview of recent developments in the quest for uncovering the molecular mechanisms involved in the pathogenesis of selected bone disease states and the role these discoveries play in the future management of bone healing and skeletal health. |
| Databáze: | OpenAIRE |
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