A Silk-Enabled Conformal Brain Electrode for Recording and Disease Treatment

Autor: Faming Zheng, Yu Zhou, Shan Zhang, Tiger H. Tao
Rok vydání: 2019
Předmět:
Zdroj: 2019 IEEE 32nd International Conference on Micro Electro Mechanical Systems (MEMS).
DOI: 10.1109/memsys.2019.8870738
Popis: We report an implantable conformal brain electrode directly on silk substrate and exploit their biomedical capabilities for neural recording and disease treatment in-vivo. A multi-layers electrode, fabricated with MEMS technology, is assembled with silk films, a dissolvable pure silk film as attaching insurance and insoluble silk film loaded with drug as function of disease treatment. This device enable real-time dynamic observation of electrocorticogram (ECoG) symptoms and spatiotemporal bioelectrical vibration across two hemispheres during epilepsy in-vivo in rat brain. The ECoG neural recording and epilepsy treatment in situ prove the great potential in multifunctional brain-machine-interface (BMI) technology for diagnosis and treatment.
Databáze: OpenAIRE