In Vitro Simulation of Flow Diverter Induced Clotting in Aneurysms Using Rennet Activated Milk Flow

Autor: Jessica M. Schmidtman, Baruch B. Lieber, Chander Sadasivan, David Fiorella, Henry H. Woo
Rok vydání: 2010
Předmět:
Zdroj: ASME 2010 Summer Bioengineering Conference, Parts A and B.
DOI: 10.1115/sbc2010-19483
Popis: Flow diverters are currently being evaluated in patients with cerebral aneurysms. Blood cells (such as platelets) contact the device mesh as they enter the aneurysm and pro-coagulant factors released by these activated cells accumulate within the aneurysm because of the intra-aneurismal flow stasis created by the device. The efficacy of any flow diverter is thus related to the rate at which blood coagulation factors accumulate within the aneurysm and get converted to thrombus.Copyright © 2010 by ASME
Databáze: OpenAIRE