Epilepsy mortality in Wales during COVID-19

Autor: Helen Daniels, Arron S Lacey, David Mikadze, Ashley Akbari, Beata Fonferko-Shadrach, Joe Jolling-Hurst, Mark I Rees, Robert H Powell, Michael P Kerr, William Owen Pickrell
Rok vydání: 2022
Předmět:
Zdroj: Journal of Neurology, Neurosurgery & Psychiatry. 93:e2.157
ISSN: 1468-330X
0022-3050
DOI: 10.1136/jnnp-2022-abn2.24
Popis: PurposeWe aimed to compare mortality rates in people with epilepsy in Wales during the pandemic with pre-pandemic rates.MethodsWe performed a retrospective study using population-scale anonymised health records. We identified deaths in people with epilepsy (DPWE), those with a diagnosis of epilepsy, and deaths associ- ated with epilepsy (DAE), where epilepsy was recorded as a cause of death. We compared death rates in 2020 with average rates in 2015–2019 using Poisson models.ResultsThere were 188 DAE and 628 DPWE in Wales in 2020 (death rates: 7.7/100,000/year and 25.7/100,000/year). The average rates for DAE and DPWE from 2015 to 2019 were 5.8/100,000/year and 23.8/100,000/year, respectively. Death rate ratios (2020 compared to 2015–2019) for DAE were 1.34 (95%CI 1.14–1.57, pConclusionsThe significant increase in DAE in Wales during 2020 could be explained by the direct effect of COVID-19 infection. Non-COVID-19 deaths have not increased significantly but further work is needed to assess the longer-term impact.
Databáze: OpenAIRE