Radiolabelled Platelet Interactions with Damaged Endothelium in the Carotid Artery of Rabbits

Autor:	D. A. J. Galvin, R. A. Harper, A. C. Meek, C. H. McCollum
Rok vydání:	1990
Předmět:	medicine.medical_specialty Intimal hyperplasia Endothelium business.industry Carotid arteries Operative mortality Balloon catheter medicine.disease medicine.anatomical_structure Internal medicine cardiovascular system Cardiology Medicine Platelet Constant infusion business Vein
Zdroj:	Clinical Application of Radiolabelled Platelets ISBN: 9789401067492
Popis:	Animals have provided models in the field of research into platelet kinetics and atherosclerosis with various methods used to inflict endothelial damage on the arterial wall. Isolation of the carotid artery with standardised ischaemic time was advocated by Buchanan & Hirsch (3) and balloon catheter damage has been used in the rabbit aorta (5) and carotid artery (9). Constant infusion of homocystine has been shown to cause endothelial damage (6) as does dietary induced hyperchlorestolaemia (1). Carotid interposition vein grafting produces a reliable model producing intimal hyperplasia, but this resulted in a high operative mortality (8).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f891c296721cbeb4e45d47dfdb016c25 https://doi.org/10.1007/978-94-009-0581-8_16 Zobrazit plný text záznamu