Keloid treatment: what about adjuvant radiotherapy?
| Autor: | Eva Meia Rüegg, Ilias G Petrou, Ali Modarressi, Brigitte Pittet-Cuénod, Thomas Zilli, Kheeldass Jugun |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adjuvant radiotherapy
medicine.medical_specialty Erythema business.industry medicine.medical_treatment Scars Dermatology medicine.disease Surgery Radiation therapy 030207 dermatology & venereal diseases 03 medical and health sciences Regimen 0302 clinical medicine Port (medical) Keloid 030220 oncology & carcinogenesis medicine medicine.symptom business Adjuvant |
| Zdroj: | Clinical, Cosmetic and Investigational Dermatology. 12:295-301 |
| ISSN: | 1178-7015 2005-2014 |
| DOI: | 10.2147/ccid.s202884 |
| Popis: | Background: Keloids are debilitating fibrous skin proliferations with a high recurrence rate after surgical treatment. Postoperative radiotherapy (PORT) is a well-tolerated adjuvant treatment to reduce the risk of recurrence, but the optimal regimen for this combined treatment remains unknown. The aim of this study is to evaluate the efficacy of combining surgical excision and immediate PORT. Methods: We retrospectively reviewed the records of patients with keloid lesions treated with adjuvant PORT in the period 2005-2014 at Geneva University Hospitals. Main outcomes were the rates of complications and recurrence in patients with a minimal follow-up of 1 year, including the Patient and Observer Scar Assessment Scale satisfaction scores. Results: 10 patients with 16 keloids were eligible (mean follow-up, 37 months). Only one recurrence was reported (6%). In 12.5% of cases, mild erythema appeared in the early postoperative period. No major complications were observed. The overall patient and observer satisfaction rate was excellent. Conclusion: Surgical excision combined with immediate PORT is an effective and easy treatment with good esthetic results and an acceptable recurrence rate. It should be considered for patients with persistent keloid formation after failure of other treatments and those at high risk of relapse. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|