New bioactive constituents characterized by LC–MS/MS in optimized microwave extract of jujube seeds (Zizyphus lotus L.)
| Autor: | Farid Dahmoune, Maria Luísa Serralheiro, Khodir Madani, Amina Abbou, Farida Berkani, Asma Ressaissi, Sofiane Dairi, Hocine Remini, Nabil Kadri |
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| Rok vydání: | 2021 |
| Předmět: |
Chromatography
Resolution (mass spectrometry) Central composite design Chemistry General Chemical Engineering 010401 analytical chemistry Extraction (chemistry) 04 agricultural and veterinary sciences Tandem mass spectrometry 040401 food science 01 natural sciences Industrial and Manufacturing Engineering 0104 chemical sciences Solvent chemistry.chemical_compound 0404 agricultural biotechnology Xanthone Response surface methodology Safety Risk Reliability and Quality Citric acid Food Science |
| Zdroj: | Journal of Food Measurement and Characterization. 15:3216-3233 |
| ISSN: | 2193-4134 2193-4126 |
| DOI: | 10.1007/s11694-021-00903-z |
| Popis: | The present study was aimed to optimize the extraction conditions of total phenolic contents (TPC) from Zizyphus lotus seeds (Zls) samples by microwave procedure using response surface methodology in order to obtain maximum extraction yields. Central Composite Design was employed with three factors defined as solvent concentration (X1), irradiation power (X2) and microwave power (X3) at three coded levels on the TPC recovery. The optimal conditions for X1, X2 and X3 were: ethanol 60%, 210 s and 600 W, respectively. The experimental value of TPC yields was for 6709.01 ± 2.20 mg GAE/100 g which is in close agreement with the predicted value indicating the model success. Results showed that optimized Zls extract exhibited a high inhibitory effect on some biological activities including antioxidants and enzyme inhibition. The liquid chromatography-high resolution tandem mass spectrometry profile revealed 47 active compounds where 21 were never been detected in Zizyphus genus. The Zls extract was found to contain significant major compounds comprised 6-methyl-2-O-glucoside xanthone, jasminoside isomer, citric acid, gallocatechin, imidazole carboxylate derivative, kaempferol-3-O-robinobioside, 6-gingerol, 2-hydroxy-2-methyl-1-[4-[3-(2,4,5-trihydroxyhexan-3-yloxy)propyl]phenyl]propan-1-one, 3-(decyloxy)-2-hydroxy-propyl prop-2-enoate, tenasogenin and some small peptides. The findings demonstrated the beneficial application of microwave method for an increase extraction of TPC amounts from Zls extracts that could be valorized in food and pharmaceutical industries. |
| Databáze: | OpenAIRE |
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