Cardiac conduction abnormalities in Reiter's syndrome
Autor: | Joseph Lindsay, Werner F. Barth, Gary B. Ruppert |
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Rok vydání: | 1982 |
Předmět: |
musculoskeletal diseases
medicine.medical_specialty Ankylosing spondylitis Pathology Heart block business.industry Cardiac conduction abnormalities Left bundle branch block Cardiomyopathy Arthritis Reiter's syndrome General Medicine Disease medicine.disease Internal medicine medicine Cardiology skin and connective tissue diseases business |
Zdroj: | The American Journal of Medicine. 73:335-340 |
ISSN: | 0002-9343 |
DOI: | 10.1016/0002-9343(82)90719-7 |
Popis: | Reiter's syndrome was found in three men who presented with cardiac conduction disturbances. In two patients, Reiter's syndrome had been present for more than 30 years and had been previously unrecognized. These patients included a 67 year old man with complete heart block of 13 years' duration, and his son, who had left bundle branch block and chronic generalized cardiomyopathy. A chart review of 19 other patients with Reiter's syndrome who were seen at this institution disclosed five patients with conduction abnormalities. Transient first-degree heart block was the most common disturbance detected and was usually associated with active Reiter's syndrome. Some conduction abnormalities appeared after a long latent period at a time when other manifestations of Reiter's syndrome were inactive. An association with this disorder was therefore not obvious. In all five patients with Reiter's syndrome and conduction disturbances, testing for B27 antigen gave positive results. Both clinical and histopathologic changes in the heart in Reiter's syndrome are analogous to those in ankylosing spondylitis, also associated with B27 antigen. We suggest that the heart, like the joints and iris, may be a target organ for B27-associated disease by a mechanism that remains to be defined. |
Databáze: | OpenAIRE |
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