A Lipoate-Protein Ligase Is Required for De Novo Lipoyl-Protein Biosynthesis in the Hyperthermophilic Archaeon Thermococcus kodakarensis

Autor:	Jian-qiang Jin, Takaaki Sato, Shin-ichi Hachisuka, Haruyuki Atomi
Rok vydání:	2022
Předmět:	Ecology Applied Microbiology and Biotechnology Food Science Biotechnology
Zdroj:	Applied and Environmental Microbiology. 88
ISSN:	1098-5336 0099-2240
DOI:	10.1128/aem.00644-22
Popis:	Based on previous studies in bacteria and eukaryotes, lipoate-protein ligases (Lpls) have been considered to be involved exclusively in lipoate salvage. The genetic analyses in this study on the lipoate-protein ligase in T. kodakarensis , however, suggest otherwise and that the enzyme is additionally involved in de novo protein lipoylation.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f864275f46341eccfa053cb229d3b5eb https://doi.org/10.1128/aem.00644-22 Zobrazit plný text záznamu