AT1-RECEPTOR BLOCKADE AFTER SHORT-TERM L-NAME AND SALT OVERLOAD PREVENTS INNATE IMMUNITY ACTIVATION AND STRONGLY ATTENUATES THE LATE DEVELOPMENT OF CHRONIC KIDNEY DISEASE

Autor:	Simone Costa Alarcon Arias, Roberto Zatz, Victor Ferreira Ávila, Clarice Kazue Fujihara, Niels Olsen Saraiva Camara, Fernanda Florencia Fregnan Zambom, Amanda Helen Albino, Karin Carneiro de Oliveira, Denise Maria Avancini Costa Malheiros
Rok vydání:	2019
Předmět:	medicine.medical_specialty Innate immune system Late development Physiology business.industry medicine.disease Endocrinology At1 receptor blockade Renal injury Internal medicine Internal Medicine medicine Cardiology and Cardiovascular Medicine business After treatment Kidney disease
Zdroj:	Journal of Hypertension. 37:e260
ISSN:	0263-6352
DOI:	10.1097/01.hjh.0000573320.67036.38
Popis:	Objective:We showed previously (AJPRenal 2006) that short-term NO inhibition by L-NAME (N) and salt overload (HS) promotes severe hypertension and renal injury that regress after treatment is ceased, but progress slowly to chronic kidney disease (CKD) thereafter. Here we investigated whether angiote
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f845b2ac543ed5adc33b5c04e60473a1 https://doi.org/10.1097/01.hjh.0000573320.67036.38 Zobrazit plný text záznamu