Recent Advances in the Dehydrogenase Biosensors Based on Carbon Nanotube Modified Electrodes

Autor:	Jian-Guo Shi, Yi-Wei Li, Qiu-Shun Li, Cui-Hua Qi, Yuan-Xiu Wang, Yao-Hong Ma, Yan Chen
Rok vydání:	2014
Předmět:	biology Chemistry Nanotechnology Dehydrogenase Carbon nanotube Overpotential Nicotinamide adenine dinucleotide Electrochemistry Combinatorial chemistry Amperometry Cofactor Analytical Chemistry law.invention chemistry.chemical_compound law biology.protein Biosensor
Zdroj:	Chinese Journal of Analytical Chemistry. 42:759-765
ISSN:	1872-2040
Popis:	Nicotinamide adenine dinucleotide (NADH) is involved as a cofactor in over 300 enzymatic reaction of NAD + /NADH dependent dehydrogenases. The application of amperometric NADH sensors has evolved to provide a promising measurement technique for detection of substrate or enzymatic activity. However, the direct oxidation of NADH at ordinary electrodes often requires high overpotential and suffers from low sensitivity and the fouling of the electrode surface by its oxidation products. In recent years, carbon nanotubes (CNT) are attracting growing attention in decreasing the high overpotential for NADH oxidation and minimizing the surface fouling. This paper introduces the research progress of the NADH electrochemical sensors based on CNT-modified electrodes, and foretells its application prospect.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f84580cda4ac4277100dc1edc0778e57 https://doi.org/10.1016/s1872-2040(13)60733-1 Zobrazit plný text záznamu Full Text from ScienceDirect