Saccharomyces boulardii CNCM I-745changes lipidemic profile and gut microbiota in a hamster hypercholesterolemic model

Autor:	X Roux, T Sulpice, F Briand, P Giammarinaro
Rok vydání:	2019
Předmět:	Microbiology (medical) biology Cholesterol Oxalobacter Hamster Context (language use) Gut flora Pharmacology biology.organism_classification Microbiology law.invention Probiotic chemistry.chemical_compound chemistry law ABCG5 biology.protein Saccharomyces boulardii
Zdroj:	Beneficial Microbes. 10:555-567
ISSN:	1876-2891 1876-2883
Popis:	Hypercholesterolemia is a main risk factor of cardiovascular disease. Probiotics are a safe approach to reduce elevated cholesterol without any deleterious effect to human health. Saccharomyces boulardii CNCM I-745 probiotic properties are well documented in a context of intestinal dysbiosis. Recent in vitro and preclinical studies have suggested its potential effects on dyslipidemia. This is the first controlled study investigating the effects of S. boulardii CNCM I-745 on lipidemic profile and gut microbiota in a hamster hypercholesterolemic model. Daily administration (3 g/kg) of S. boulardii for 21 or 39 days in hamsters fed a 0.3% cholesterol-diet significantly reduced total plasma cholesterol (P
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::f8366b7a3151a2da62ab68e05d45d344 https://doi.org/10.3920/bm2018.0134 Zobrazit plný text záznamu