Spiroalkylation of some Homophthalimides and Oxindoles with 1-Bromo-2-chloroethane

Autor:	D. E. Horning, G. Lacasse, J. M. Muchowski
Rok vydání:	1971
Předmět:	Chemistry Organic Chemistry Organic chemistry General Chemistry Alkylation 1-bromo-2-chloroethane Catalysis
Zdroj:	Canadian Journal of Chemistry. 49:246-254
ISSN:	1480-3291 0008-4042
DOI:	10.1139/v71-043
Popis:	The base-induced alkylation of 4-unsubstituted homophthalimides with 1-bromo-2-chloroethane produced the spirocyclopropane compounds 4. The structures of these compounds were supported by their spectral properties and by their susceptibility towards cleavage of the three-membered ring with secondary amines.Under similar conditions, 3-unsubstituted oxindoles also yielded spirocyclopropane compounds 7, but 4-hydroxycarbostyril gave the 4-O-alkylated compound 8 instead.
Databáze:	OpenAIRE
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