Monophasic Action Currents from the Uninjured Turtle Ventricle

Autor: Richard Ashman, Norman C. Woody
Rok vydání: 1939
Předmět:
Zdroj: Experimental Biology and Medicine. 42:17-20
ISSN: 1535-3699
1535-3702
DOI: 10.3181/00379727-42-10784
Popis: Monophasic action currents obtained by derivation from 2 uninjured points on heart muscle have often been mentioned in the literature. Samojloff,1 for example, produced a block by transverse cutting or compression of the frog heart and recorded monophasic action currents by derivation from uninjured base and apex. In this experiment, however, the apical muscle constitutes an extension of the lead to the injured surface. DeBoer2 has recently stressed his observation that, employing base-apex leads in the frog, the weak beat in alternation may be associated with monophasic action currents. Although no injury was produced in these experiments by mechanical means, the blocking of the impulse must have been due to the presence of muscle in an abnormal physiological state. Gilson3 has recorded monophasic action currents following injury, but at a time when the demarcation current had shrunk practically to zero.In our observations, which are incidental to a study of the action currents of the turtle heart, monop...
Databáze: OpenAIRE