Medical management of Cushing's disease
| Autor: | John Newell-Price, Alan Kelsall |
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| Rok vydání: | 2021 |
| Předmět: | |
| DOI: | 10.1016/b978-0-12-819949-7.00046-9 |
| Popis: | Steroidogenesis inhibitors such as ketoconazole and metyrapone remain the mainstay in the medical management of Cushing's disease. Pituitary-directed therapies, including dopamine receptor antagonists and more recently somatostatin receptor agonists, can also be implemented with varying rates of success. Newer agents such as osilodrostat and levoketoconazole are currently in development and recent studies have shown promising results. We review current medical therapies for Cushing's disease along with common adverse effects and monitoring requirements. |
| Databáze: | OpenAIRE |
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