Acute respiratory infections due to enterovirus 68 in Yamagata, Japan between 2005 and 2010

Autor: Hitoshi Oshitani, Tadayuki Ahiko, Tsutomu Itagaki, Yoko Matsuzaki, Chieko Abiko, Yoko Aoki, Yuriko Katsushima, Masahiro Noda, Katsumi Mizuta, Fumio Katsushima, Hirokazu Kimura, Tadatsugu Imamura, Naoko Fuji, Tatsuya Ikeda
Rok vydání: 2012
Předmět:
Zdroj: Microbiology and Immunology. 56:139-143
ISSN: 0385-5600
Popis: To clarify the epidemiology of enterovirus 68 (EV68), which is one of the most rarely identified enteroviruses, virus isolation and molecular screening using RT-PCR was performed on 6307 respiratory specimens collected at pediatric clinics in Yamagata, Japan between 2005 and 2010. In the years 2005-2009, 10, 1, 2, 0, and 2 (40) EV68-positive cases, respectively, were identified by RT-PCR. In 2010, 40 cases were identified altogether: 2 by isolation only, 26 by RT-PCR only, and 12 by both isolation and RT-PCR. Phylogenetic analysis indicated that plural genetically distinct clusters co-circulated. These results suggest that that difficulty in EV68 isolation leads to an underestimation of the prevalence of EV68 infections.
Databáze: OpenAIRE