Studies on the Synthesis of Sesquiterpene Lactones, 16. The Syntheses of 11β,13-Dihydrokauniolide, Estafiatin, Isodehydrocostuslactone, 2-Oxodesoxyligustrin, Arborescin, 1,10-Epiarborescin, 11β,13-Dihydroludartin, 8-Deoxy-11β,13-dihydrorupicolin B, 8-Deoxyrupicolin B, 3,4-Epiludartin, Ludartin, Kauniolide, Dehydroleucodin, and Leucodin
| Autor: | Naoki Minami, Koji Isogai, Kunihiko Ibayashi, Tomomasa Nakamura, Hideki Yoshimura, Masayoshi Ando |
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| Rok vydání: | 1994 |
| Předmět: |
Pharmacology
chemistry.chemical_classification Chemistry Stereochemistry Organic Chemistry Cationic polymerization Pharmaceutical Science Epoxide Sesquiterpene Analytical Chemistry chemistry.chemical_compound Complementary and alternative medicine Drug Discovery Dehydroleucodin Molecular Medicine Organic chemistry Solvolysis Arborescin Lactone |
| Zdroj: | Journal of Natural Products. 57:433-445 |
| ISSN: | 1520-6025 0163-3864 |
| DOI: | 10.1021/np50106a001 |
| Popis: | A total of eleven naturally occurring guaianolides, 11β,13-dihydrokau- niolide, estafiatin, isodehydrocostuslactone, 2-oxodesoxyligustrin, arborescen, 11β,13-dihydroludartin, 8-deoxy-11b,13-dihydrorupicolin B, ludartin, kauniolide, dehydroleucodin, and leucodin, and three related compounds, 1,10-epiarborescin, 8-deoxyrupicolin B, and 3,4-epiludartin, were synthesized through a common cationic intermediate A, which was derived from (11S)-1β-(mesyloxy)eudesm-3-eno-12,6α-lactone [2] by solvolytic rearrangement |
| Databáze: | OpenAIRE |
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