Characterization of Two Kinds of Lactotransferrin (Lactoferrin) Receptors on Different Target Cells
| Autor: | B. Leveugle, Takashi Mikogami, Annick Pierce, Elisabeth Rochard, Joël Mazurier, Dominique Legrand, Geneviève Spik, Jean Montreuil |
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| Rok vydání: | 1994 |
| Předmět: |
chemistry.chemical_classification
0303 health sciences Growth factor medicine.medical_treatment Cell Lactoferrin receptors Immune receptor Biology 3. Good health Cell biology Lactotransferrin 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure chemistry Biochemistry medicine Glycoprotein High affinity receptor Receptor 030304 developmental biology 030215 immunology |
| Zdroj: | Lactoferrin Structure and Function ISBN: 9780306447341 |
| DOI: | 10.1007/978-1-4615-2548-6_2 |
| Popis: | Lactotransferrin (Lf), an iron-binding glycoprotein present as a major component in the specific granules of human neutrophilic granulocytes is released in the blood during the acute phase of infection and participates in the regulation of the host-defence mechanisms. Our previous observations (Mazurier et al., 1989) showing i) that the activation by PHA of T-lymphocytes induces the appearance at the cell surface of Lf-receptors which are absent from the membrane of resting lymphocytes and ii) that Lf becomes a growth factor for the activated lymphocytes, led us to undertake a series of researches on the presence of Lf receptors at the surface of different blood cells. |
| Databáze: | OpenAIRE |
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