Synthesis of TN and T Antigen Glycopeptide Sequences of tumor-associated MUC-1 usingS-pent-4-enyl thioglycosides

Autor:	Michael Leuck, Horst Kunz
Rok vydání:	1997
Předmět:	Antigen Tandem repeat Stereochemistry Chemistry Muc1 Mucin Glycopeptide
Zdroj:	Journal für Praktische Chemie/Chemiker-Zeitung. 339:322-334
ISSN:	1521-3897 0941-1216
DOI:	10.1002/prac.19973390160
Popis:	The synthesis of glycopeptides 34 and 38 with tumor associated TN and T antigen structure containing a partial sequence of the tandem repeat unit of the polymorphic epithelial mucin MUC-1 were achieved via fragment condensations. Electrophilic activation of S-pent-4-enyl thioglycosides was appiled for the construction of O-glycosyl amino and saccharide building blocks.
Databáze:	OpenAIRE
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