Abnormal Thymocyte Development and Neurofilament-Reactive Thymocytes in Thymoma

Autor: Alexander Marx, Socrates J. Tzartos, A. Schultz, Viola Hoffacker, R Nenninger, Hans Konrad Müller-Hermelink
Rok vydání: 2000
Předmět:
Zdroj: Myasthenia Gravis ISBN: 9789401057875
DOI: 10.1007/978-94-011-4060-7_6
Popis: Myasthenia gravis (MG) is an autoimmune disease caused by autoantibodies against the acetylcholine receptor (AChR) at the neuromuscular junction [1, 2]. Mature CD4+ T-cells are involved in the production of these antibodies [3, 4]. The destruction at the neuromuscular endplates leads to the clinical symptom of muscle weakness.
Databáze: OpenAIRE