Abnormal Thymocyte Development and Neurofilament-Reactive Thymocytes in Thymoma
Autor: | Alexander Marx, Socrates J. Tzartos, A. Schultz, Viola Hoffacker, R Nenninger, Hans Konrad Müller-Hermelink |
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Rok vydání: | 2000 |
Předmět: | |
Zdroj: | Myasthenia Gravis ISBN: 9789401057875 |
DOI: | 10.1007/978-94-011-4060-7_6 |
Popis: | Myasthenia gravis (MG) is an autoimmune disease caused by autoantibodies against the acetylcholine receptor (AChR) at the neuromuscular junction [1, 2]. Mature CD4+ T-cells are involved in the production of these antibodies [3, 4]. The destruction at the neuromuscular endplates leads to the clinical symptom of muscle weakness. |
Databáze: | OpenAIRE |
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