Mural thrombi in the heart

Autor: Curtis F. Garvin
Rok vydání: 1941
Předmět:
Zdroj: American Heart Journal. 21:713-720
ISSN: 0002-8703
DOI: 10.1016/s0002-8703(41)90800-1
Popis: Of 771 consecutive, adult, autopsied patients who died of heart disease, 265, or 34.4 per cent, had one or more mural thrombi. Coronary artery disease, with myocardial infarction, was the type of heart disease most often associated with mural thrombi; in two-thirds of these cases this complication was present. Mural thrombi were associated with coronary artery disease without myocardial infarction, hypertensive heart disease, and rheumatic heart disease, in one-third of the cases; they were present in one-fifth of the cases of syphilitic heart disease, but were uncommonly found in cases of cor pulmonale and bacterial endocarditis. Most of the mural thrombi in cases of coronary artery disease with myocardial infarction were caused by the infarction itself and were located in the left ventricle. In hypertensive heart disease, about 60 per cent of the patients below 40 years of age had mural thrombi, whereas only 20 per cent of those who were 60 years of age or older had this complication. This significant difference is unexplained. In rheumatic heart disease, mural thrombi occurred two and a half times as often in patients with auricular fibrillation as in those with normal mechanism; this is highly significant. The thrombi were present in the right atrium and/or the left atrium in 86.5 per cent of the cases, and this is probably another indication of the importance of auricular fibrillation. There was a highly significant preponderance of mural thrombi in older patients, presumably because of the greater frequency of auricular fibrillation in this group.
Databáze: OpenAIRE
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