Treatment with Intensity-Modulated Radiation Therapy (IMRT) and Chemotherapy in Advanced Inoperable Non-Small Cell Lung Cancer (NSCLC): Toxicity, Survival and Patterns of Failure in Relation to Treatment with High and Low Radiation Dose
| Autor: | Kent Armeson, John Stahl, Anand K. Sharma, Tarek A. Dufan, Aaron Luebke, James K. Russo, John T. Reynolds, Daniel Grass |
|---|---|
| Rok vydání: | 2015 |
| Předmět: |
education.field_of_study
Chemotherapy medicine.medical_specialty Lung business.industry medicine.medical_treatment Population non-small cell lung cancer (NSCLC) medicine.disease medicine.anatomical_structure Toxicity Medicine Radiology business education Lung cancer Nuclear medicine Esophagitis Pneumonitis |
| Zdroj: | Journal of Cancer Therapy. :943-953 |
| ISSN: | 2151-1942 2151-1934 |
| DOI: | 10.4236/jct.2015.611102 |
| Popis: | Purpose: To investigate the toxicity, survival and patterns of failure in patients with advanced lung cancer treated with intensity modulated radiation therapy (IMRT) and chemotherapy. Methods and Materials: Retrospective chart review of 68 total patients: 46 academic and 22 community center. Endpoints: Grade ≥ 3 pneumonitis, Grade ≥ 2 esophagitis, local, regional and distant failure, progression-free survival (PFS) and overall survival (OS). Results: For the academic center patients, median follow-up was 19.2 months. Esophagitis: 0% Grade 3, 35% Grade 2, no significant difference between dose bins |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|