A CASE OF ESOPHAGEAL CANCER WITH IDIOPATHIC THROMBOCYTOPENIC PURPURA (ITP)

Autor:	Teruyuki Sakaguchi, Yukishige Yamada, Yukiyasu Kuzumoto, Hiroshige Nakano, Akihiko Watanabe
Rok vydání:	1999
Předmět:	medicine.medical_specialty idiopathic thrombocytopenic purpura (ITP) business.industry medicine.medical_treatment Splenectomy Esophageal cancer Anastomosis medicine.disease Thrombocytopenic purpura Surgery medicine Platelet business Adverse effect Complication
Zdroj:	Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association). 60:1537-1541
ISSN:	1882-5133 1345-2843
DOI:	10.3919/jjsa.60.1537
Popis:	A 67-year-old man was referred to the department with a diagnosis of esophageal cancer. On admission, a decrease in platelet count, 6.2×10/m3 and a slight increase in PAIgG were noted. So the patient was diagnosed as having idopathic thrombocytopenic purpura (ITP) as well. The patient underwent high-dose γ-globulin therapy (286mg/kg/day) for 5 consecutive days prior to surgery. After confirming an increase in platelet count from 6.2×104 to 16.7×104/mm3, the patient safely underwent a subtotal esophagectomy, regional lymph node dissection (R3) and splenectomy. Although anastomotic insufficiency occurred, the complication was cured without surgical procedure. We believe that the high-dose γ-globulin therapy that is able to increase platelets in a short time and has minimal adverse effects is very useful in preoperative management of the patients with esophageal cancer with ITP.
Databáze:	OpenAIRE
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