Antimicrobial effect of ozone therapy on root canal system: an integrative review

Autor: Fernandes, Bárbara Silva, Lacerda, Mariane Floriano Lopes Santos, De Lima, Carolina Oliveira, Girelli, Caroline Felipe Magalhães
Rok vydání: 2023
Předmět:
DOI: 10.17605/osf.io/b8qs4
Popis: This study aimed to verify the available literature on the efficacy of ozone therapy on endodontic treatment and the most indication form of application during root canal preparation. Material and Methods: The sources analyzed included the PubMed/MEDLINE, Scopus, Web of Science, Lilacs and BBO databases, through search strategies through a combination of descriptors: ozone, root canal therapy and antimicrobial agent. The eligibility criteria used to select these articles were: articles available in full in the searched database and published until November 2022, and that addressed the following inclusion criteria: investigation of the antimicrobial effect of ozone therapy during endodontic treatment and/or its most indication form of application or use. 27 articles were included in the integrative review and data extracted from the studies were tabulated. Results: most of the studies demonstrated that isolated ozone, whether in gaseous or aqueous form, has a significant antibacterial effect on root canals as an adjuvant method, but not enough to be used as the only disinfection modality. Sodium hypochlorite (NaOCl) showed a greater antimicrobial effect than ozone in most studies, being the most indicated irrigating solution. The association of gaseous ozone and 2.5% NaOCl is the most common form of application during root canal treatment. Conclusion: The ozone therapy, when associated with conventional auxiliary substances, such as NaOCl, proved to be a potent adjuvant method in endodontic treatment to reduce microorganisms in the root canal system and can be used in the presentation of gas, water, or gel. However, when used alone did not show benefits in terms of antimicrobial efficacy during treatment. It is suggested, therefore, the development of randomized clinical trials, to obtain a standardization of the clinical protocol for the application of ozone in association with irrigating substances during endodontic treatment.
Databáze: OpenAIRE